Chronic constipation can lead to fecal impaction in the large bowel, which can cause pressure necrosis followed by perforation, known as a stercoral ulcer.In extensive posterior thoracolumbar surgery, a long operation time, large blood loss, and perioperative narcotic use may aggravate constipation.Moreover, sacral root palsy due to cauda equina sy
Assessment of search strategies in Medline to identify studies on the impact of long COVID on workability
ObjectivesStudies on the impact of long COVID on work capacity are increasing but are difficult to locate in bibliographic databases, due to the heterogeneity of the terms used to describe this new condition and its consequences.This study aims to report on the effectiveness Folding Knives of different search strategies to find studies on the impac
Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity
In response to activating signals, transcription factors (TFs) bind DNA and regulate gene expression.TF binding can be measured by protection of the bound sequence from DNase digestion (i.e., footprint).Here, we report that 80% of TF binding motifs do not show a measurable footprint, partly because of a variable cleavage pattern within the motif se
Detection and elimination of Proteus vulgaris and Klebsiella pneumoniae in nude mice
Introduction: Nude mice are immunodeficient, commonly used model organisms for studying human diseases.Despite the high purchase price and maintenance cost of these animals, few studies have aimed to eradicate inevitable infectious complications which may arise during in-vivo studies.The current project is a practical guideline for detecting and el
Bothrops jararaca venom metalloproteinases are essential for coagulopathy and increase plasma tissue factor levels during envenomation.
BACKGROUND/AIMS:Bleeding tendency, coagulopathy and platelet disorders are recurrent manifestations in snakebites occurring worldwide.We reasoned that by damaging tissues and/or activating cells at the site of the bite and systemically, snake venom toxins might release or decrypt tissue factor (TF), resulting in activation of blood coagulation and